diff --git a/CMakeLists.txt b/CMakeLists.txt
index 1cc83a2..9927bc7 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -72,6 +72,13 @@ else()
 endif()
 
 set(USB_ITF_HID 1)
+
+option(WAVESHARE_RP2350_ONE "Enable Waveshare RP2350-One LED support" OFF)
+if(WAVESHARE_RP2350_ONE)
+    add_definitions(-DWAVESHARE_RP2350_ONE=1)
+    message(STATUS "Waveshare RP2350-One: \t enabled")
+endif()
+
 include(pico-keys-sdk/pico_keys_sdk_import.cmake)
 
 if(NOT ESP_PLATFORM)
diff --git a/README.md b/README.md
index 77f34ce..2bfd17d 100644
--- a/README.md
+++ b/README.md
@@ -74,6 +74,7 @@ PICO_SDK_PATH=/path/to/pico-sdk cmake .. -DPICO_BOARD=board_type -DUSB_VID=0x123
 make
 ```
 Note that `PICO_BOARD`, `USB_VID` and `USB_PID` are optional. If not provided, `pico` board and VID/PID `FEFF:FCFD` will be used.
+For Waveshare RP2350-One board, add `-DWAVESHARE_RP2350_ONE=ON` to enable RGB LED support on GPIO 16.
 
 Additionally, you can pass the `VIDPID=value` parameter to build the firmware with a known VID/PID. The supported values are:
 
@@ -117,6 +118,18 @@ While processing, the Pico FIDO is busy and cannot receive additional commands u
 
 ![Processing](https://user-images.githubusercontent.com/55573252/162009007-df45111e-2473-4a92-97c5-15c3cd19babd.gif)
 
+### Waveshare RP2350-One RGB LED
+
+The Waveshare RP2350-One uses a WS2812 RGB LED on GPIO 16. Different colors indicate different states:
+
+| State            | Color     | Pattern                         |
+| ---------------- | --------- | ------------------------------- |
+| Not mounted      | 🔴 Red    | 500ms on / 500ms off            |
+| Mounted (active) | 🟢 Green  | 500ms on / 500ms off            |
+| Suspended (idle) | 🔵 Blue   | 1000ms on / 2000ms off          |
+| Processing       | 🟢 Green  | 50ms on / 50ms off (fast blink) |
+| Press to confirm | 🟡 Yellow | 1000ms on / 100ms off           |
+
 ## Driver
 
 Pico FIDO uses the `HID` driver, which is present in all operating systems. It should be detected by all OS and browser/applications just like normal USB FIDO keys.